Jenifer

Laura San Giacomo

Jenifer Estess

Jane Kaczmarek

Valerie Estess

Annabella Sciorra

Meredith Estess

Jane Alexander

Marilyn Estess

Maddie Corman

Julianne Hoffenberg

Edie Falco

Wheelchair Saleswoman

Donna Hanover

Herself

Camryn Manheim

Nurse Vandemal

Julianna Margulies

Jenifer's Psychiatrist

Rob Morrow

Dr. Richard Feldman

Reed Rudy

Scotty

Cedric Smith

Dr. Richards

Vincent Spano

Jack

Fisher Stevens

Dr. Aaron Sanders

Marisa Tomei

Nina Capelli

Bradley White

Michael

Scott Wolf

Jenifer's Date

Colin Ferguson

Peter

Karen Robinson

Lorna

Jason Blicker

Neurologist