I Smile Back

Sarah Silverman

Laney Brooks

Josh Charles

Bruce Brooks

Thomas Sadoski

Donny

Skylar Gaertner

Eli Brooks

Chris Sarandon

Roger

Terry Kinney

Dr. Page

Mia Barron

Susan

Shayne Coleman

Janey Brooks

Kristin Griffith

Nurse Pauline

Nick Taylor

Guard

Sean Reda

Henry

Cynthia Darlow

Mrs. Kosinski

Clark Jackson

Mr. Odesky

Brian Koppelman

David Blackman

Emma Ishta

Katrina

Oona Laurence

Daisy

Mike Sharits

Bartender

Mia Katigbak

Mrs. Mattingly

Gregory Dann

Quaker State

Kevin Abernethy

Restaurant Patron (uncredited)