Middle of Nowhere

David Oyelowo

Brian

Maya Gilbert

Gina

Sharon Lawrence

Fraine

Emayatzy Corinealdi

Ruby

Dondré Whitfield

Littleton

Omari Hardwick

Derek

Lorraine Toussaint

Ruth

Andy Spencer

Bus Hustler

Edwina Findley

Rosie

Yvette Cason

Mrs. Hastings

Troy Curvey III

Rashad

Bruce Katzman

Averick

Romann Aric

Jordan

Romann Aric

Jordann

Nehemiah Sutton

Nickie

Nisa Ward

Fraine's Assistant

Maynor Lopez

Prison Guard

Marmee Regine Cosico

Prison Visitor

Bob Rumnock

Dying Cancer Patient

William 'Bill' Connor

ATF Agent (uncredited)